Time course of IL-5's (5 ng/mL) effect on Syk^−/− and wild-type fetal liver–derived cultures.

Effect on Syk^−/−, closed symbols; on wild-type, open symbols. (A) Total cell number (squares), eosinophil percentage (ovals), and mean values ± SEM from 3 independent experiments. (B) Total eosinophil numbers (triangles) were measured in cultures derived from 4 independent Syk^−/− or wild-type mice and maintained with 0.1- (dashed line), 0.5- (plain line), or 2.5-ng/mL (bold line) IL-5 for various times. Data are expressed as mean ± SEM.