Fig. 6.
Fig. 6. Release of O2− radicals by unstimulated PMNs preincubated with native supernatant of autologous degranulated PMNs, MPO-immunodepleted supernatant, or purified MPO added to buffer. / In the presence of soluble MPO during preincubation, PMNs became responsive to anti-MPO antibody, resulting in the release of O2− radicals.

Release of O2− radicals by unstimulated PMNs preincubated with native supernatant of autologous degranulated PMNs, MPO-immunodepleted supernatant, or purified MPO added to buffer.

In the presence of soluble MPO during preincubation, PMNs became responsive to anti-MPO antibody, resulting in the release of O2− radicals.

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