Comparison of α- and γ-thrombin–induced platelet procoagulant activity.

(A) Platelet procoagulant activity induced by α- or γ-thrombin; ● indicates 25 000 platelets/μL activated with 5 to 20 nmol/L α-thrombin; ○, 25 000 platelets/μL activated with 50 to 200 nmol/L γ-thrombin. (B) CD62 expression on α- and γ-thrombin–activated gel-filtered platelets; ● indicates 25 000 platelets/μL activated with 5 to 20 nmol/L α-thrombin; ○, 25 000 platelets/μL activated with 50 to 200 nmol/L γ-thrombin. The fluorescence of 5000 platelets per measuring point was determined by flow cytometry. Data are the mean of 3 experiments using platelets from different donors.