Induction of IL-8 secretion by HrHRF alone in eosinophils primed with GM-CSF.

Eosinophils were treated with GM-CSF and placed in medium alone or with 0.7 μmol/L HrHRF, and the supernatants were tested for IL-8 content. Twelve experiments using samples from 7 donors are represented. Each experiment is plotted; the same symbol is used to depict samples from the same donor. There was a significant difference in IL-8 production between HrHRF-stimulated cells and controls (P < .03).