Sequence of the CCR3 promoter.

The 2.7-kb 5′ BglII fragment (Figure 3) was fully sequenced. The exon 1 is bolded. The splice donor consensus sequence is double-underlined. Numbering is based on assigning +1 to the first base of the longest 5′-RACE product. Underlined are restriction enzyme sites (BglII, KpnI); overlined are consensus transcription factor binding sites; boxed are pyrimidine-rich sequences; the shaded box depicts the area of high homology with CCR2 that contains the Alu repeat and the light gray box marks the area of homology with hIL-5Rα. The asterisk depicts the site of the identified polymorphism.