Longitudinal evaluation of HHV8 DNA copy numbers in PBMCs, serum CRP, plasma IL-6, and plasma IL-10.

Longitudinal evaluation of HHV8 DNA copy numbers in PBMCs, serum CRP, plasma IL-6, and plasma IL-10 in 3 patients shows a strong correlation between these 4 covariates in patient 2 (A) within 15 visits over a 25-month period and in patient 13 (B) within 10 visits over a 24-month period. Panel (C) shows a dramatic decrease in all biological markers during the first 4 weeks following the initiation of chemotherapy in patient 3.