Recombinant vIL-10 and hIL-10 inhibit postcapillary venular endothelial cell proliferation.

Synchronized and subconfluent endothelial cells were cultured with test substances (VEGF or FGF-2) in the absence or in the presence of vIL-10 (A) or hIL-10 (B) for 48 hours. Thereafter, the cells were counted. Data are means ± SEM of 4 experiments. *P < .05 versus proliferation in the absence of IL-10 (Studentt test).