Fig. 3.
IL-10 inhibits tumor growth locally.
The 107 cells from hIL-10 DG75 subline and vector control DG75 line were mixed before sc injection in the flank (■), or simultaneously injected sc in contralateral flanks in SCID mice (vector right flank, ▴; hIL-10 left flank, +). For comparison, the growth of 107 vector control cells (●) was assessed in the same experiment. Tumor growth was monitored twice a week for 42 days. n = 4. (Note: All 4 vectors coincide on days 0 and 5; the 3 noncontrol vectors coincide on day 12; and the control and right flank vectors coincide on days 35 and 42.)
