Effect of L-NMMA on the induction of the wild-type and mutated GATA motifs of the Epo promoter/enhancer with Luc reporter constructs in Hep3B cells.

Wild-type (Pwt) and mutated (Pm7) GATA motifs. Hypoxic induction of Luc gene expression is represented as a hypoxia/normoxia ratio. Fold induction indicates this hypoxia/normoxia ratio. Three separate experiments (duplicate sample) were performed (n = 3). Error bars represent 1 SD.