Effect of L-NAME on serum Epo from anemic mice.

Five BDF1 mice were injected intraperitoneally with 0.2 mL of 10 mg L-NAME/mL PBS or 0.2 mL of PBS. Blood samples (0.3 mL) were taken from the orbital vein at 0, 12, and 24 hours after injection of L-NAME. Serum Epo levels were determined by RIA. Error bars represent 1 SD. *P < .01.