Fig. 2.
Fig. 2. Catalase inactivation (A) and hemoglobin oxidation (B) in red cells exposed to 50 mmol/L 3-AT and a continuous flux of H2O2. / Hematocrit 10%, Krebs-Ringer buffer. The rate of H2O2 production was 0.123μmol/L per minute (circles), 0.615 μmol/L per minute (squares), and 1.23 μmol/L per minute (triangles). Solid lines, wild-type red cells; dashed lines, GSHPx-1–deficient red cells.

Catalase inactivation (A) and hemoglobin oxidation (B) in red cells exposed to 50 mmol/L 3-AT and a continuous flux of H2O2.

Hematocrit 10%, Krebs-Ringer buffer. The rate of H2O2 production was 0.123μmol/L per minute (circles), 0.615 μmol/L per minute (squares), and 1.23 μmol/L per minute (triangles). Solid lines, wild-type red cells; dashed lines, GSHPx-1–deficient red cells.

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