Fig. 2.
Fig. 2. Cytokine responsiveness of theβc null andβc/βIL3 null mice. / Responsiveness to (A) 500 U/mL G-CSF (initial concentration), (B) 4 U/mL EPO, and (C) 100 ng/mL SCF with serial 2-fold dilutions. Results are the colony number (the mean plus or minus SD) at each cytokine dilution expressed as a percentage of maximal colony number, using 1-2 mice per genotype. Similar results were seen in 3 independent experiments. A minimum of 3-4 mice were examined per genotype. Wild type is indicated by open circles and βc/βil-3 null by closed circles.

Cytokine responsiveness of theβc null andβc/βIL3 null mice.

Responsiveness to (A) 500 U/mL G-CSF (initial concentration), (B) 4 U/mL EPO, and (C) 100 ng/mL SCF with serial 2-fold dilutions. Results are the colony number (the mean plus or minus SD) at each cytokine dilution expressed as a percentage of maximal colony number, using 1-2 mice per genotype. Similar results were seen in 3 independent experiments. A minimum of 3-4 mice were examined per genotype. Wild type is indicated by open circles and βc/βil-3 null by closed circles.

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