Involvement of C1qRp in the suppressive effects of adiponectin on macrophage functions.

Human macrophages were incubated with 10 μg/mL adiponectin or HSA for 24 hours in the presence or absence of the indicated antibodies (30 μg/mL). (A) After incubation, the cells were subjected to phagocytosis assay. Significant differences from control (HSA) values are indicated by 2 (P < .01) asterisks. This figure shows 1 of 3 similar experiments. (B) After incubation, the cells were stimulated with 10 μg/mL LPS for 4 hours. Total RNAs were then isolated and subjected to Northern blot analyses. This figure shows 1 of 2 independent experiments.