Fig. 5.
Fig. 5. Progenitor and stem cell pool size after administration of 5-FU to B6 and DBA mice. / Panel A depicts the absolute number of CAFC day 7, day 14, day 21, and day 35 per femur that remain viable 24 hours after 5-FU treatment. Panel B and C show recovery kinetics expressed as percentage of normal values of respectivily marrow CAFC day 7 and day 35 numbers after administration of 5-FU. Normal values for B6 and DBA mice, respectively, are CAFC day-7, 20 to 25 × 103 and 14 to 18 × 103; CAFC day-35, 250 to 300 and 600 to 800. Error bars indicate 95% confidence intervals.

Progenitor and stem cell pool size after administration of 5-FU to B6 and DBA mice.

Panel A depicts the absolute number of CAFC day 7, day 14, day 21, and day 35 per femur that remain viable 24 hours after 5-FU treatment. Panel B and C show recovery kinetics expressed as percentage of normal values of respectivily marrow CAFC day 7 and day 35 numbers after administration of 5-FU. Normal values for B6 and DBA mice, respectively, are CAFC day-7, 20 to 25 × 103 and 14 to 18 × 103; CAFC day-35, 250 to 300 and 600 to 800. Error bars indicate 95% confidence intervals.

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