Fig. 7.
Fibrinolytic activity of scuPA/suPAR complexes in rat plasma in vitro.
Human plasma clots, trace-labeled with 125I-fibrin, were incubated in human or rat plasma supplemented with 25 nmol/L scuPA (human plasma indicated by ▪, rat plasma indicated by ■) or 25 nmol/L scuPA/suPAR (human plasma indicated by ♦, rat plasma indicated by ⋄) at 37°C. The radioactive fibrin degradation products released into the supernatant were measured at the indicated times. At each time point, fibrinolysis was calculated by subtracting the endogenous release of radioactivity and was expressed as the percent of total lysis. The data shown represent the mean plus or minus SD of triplicate determinations from 2 experiments.
