Classification of 102 AML patients according to the 2 most important independent prognostic factors, plasma nm23-H1 level and WBC count.

(A) The plasma nm23-H1 levels and WBC counts of all of the AML cases were plotted and divided into 4 groups: group A, high nm23-H1 (≥ 80 ng/mL) and low WBC count (≤ 50 000/μ); group B, high nm23-H1 (≥ 80 ng/mL) and high WBC count (> 50 000/μL); group C, low nm23-H1 (< 80 ng/mL) and low WBC count (≤ 50 000/μL); and group D, low nm23-H1 (< 80 ng/mL) and high WBC count (> 50 000/μL). The CR ratio was 28.6% in group A (n = 21), 0% in group B(n = 8), 85.7% in group C (n = 70), and 100% in group D (n = 3). (B) Kaplan-Meier survival curves of groups A, B, C, and D.