Fig. 6.
Role of perforin and FasL in CD8+T-cell–mediated GVL.
We injected B6 mice with MMB3.19 cells and lethally irradiated them the next day. These recipient mice received ATBM cells alone (n = 10) or in combination with 5 × 106 MMB3.19-primed CD8+ T cells from either wt (n = 10), pfpo (n = 15), or gld (n = 11) donor B6 mice. Survival of the mice was monitored daily until termination of the experiment. The results represent pooled data from 2 similar experiments.
