Fig. 2.
Fig. 2. t(4;14)(p16;q32) translocation in myeloma. / Derivative chromosomes 4 and 14 of myeloma. IGH breaks in this malignancy are usually found within the S regions. (A)FGFR3 expression is driven by the centromeric IGHtranscriptional enhancer (Eα) on the der(14), whileMMSET expression (B) is driven by the intronic enhancer (Eμ) on the der(4). Tel indicates telomere.

t(4;14)(p16;q32) translocation in myeloma.

Derivative chromosomes 4 and 14 of myeloma. IGH breaks in this malignancy are usually found within the S regions. (A)FGFR3 expression is driven by the centromeric IGHtranscriptional enhancer (Eα) on the der(14), whileMMSET expression (B) is driven by the intronic enhancer (Eμ) on the der(4). Tel indicates telomere.

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