Fig. 5.
Fig. 5. Uptake of 125I–IF–Cbl in cubilin-expressing epithelial cells and inhibition with the wild-type and FM1 mutant CUB 5-8 proteins. / (A) Time-course for cell association (•) and degradation (○) of iodine 125–IF–Cbl. (B) Time-course for uptake and degradation of iodine 125–IF–Cbl in the presence of chloroquine and leupeptin. Values are the mean ± 1 SD of triplicate experiments.

Uptake of 125I–IF–Cbl in cubilin-expressing epithelial cells and inhibition with the wild-type and FM1 mutant CUB 5-8 proteins.

(A) Time-course for cell association (•) and degradation (○) of iodine 125–IF–Cbl. (B) Time-course for uptake and degradation of iodine 125–IF–Cbl in the presence of chloroquine and leupeptin. Values are the mean ± 1 SD of triplicate experiments.

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