The mean rate of U937 cell locomotion is a function of LSP1 level.

(A) The mean rates of locomotion (n = 3) for 100 cells analyzed from 3 different experiments in which transfected U937 cells were induced to monocytic differentiation and then MI-U937⁻, MI-U937⁺, and MI-U937⁺⁺⁺⁺ cells were plated, videotaped, and video-tracked for 2 hours to determine their rates of locomotion. The distribution of rates of locomotion of U937 cells confirms variance of rate of locomotion with LSP1 level. (B) A comparison of the histograms of the rates of locomotion among 150 MI-U937⁻, MI-U937⁺, and MI-U937⁺⁺⁺⁺ cells.