Staining for CD4 and CD8 in spleen from case 4.

(A) Low-power view of spleen shows that the lymphoid nodules are composed predominantly of CD4⁺ cells. (B) Relatively few CD8⁺ cells are seen. (C) The CD4⁺ cells are also EBER1⁺ (immunoperoxidase stained, hematoxylin counterstained, × 50).