Effect of heparin on adherence of Plasmodium falciparum-infected erythrocytes (IEs) to human dermal microvascular endothelial cells (HDMEC).

Cytoadherence to resting HDMEC (□) and HDMEC activated by tumor necrosis factor (TNF) (▪) was determined in the absence or presence of 100 μg/mL heparin. Results are mean ± SEM value from 4 experiments. The inset shows cytoadherence to resting (×) and TNF-activated (□) HDMEC in the presence of a range of heparin concentrations. Results are the mean ± SD of value for triplicate points from 1 of 2 experiments.