Fig. 5.
Characterization of platelet activation by SDF-1, MDC, ADP, and TRAP.
(A) TxB2 formation (gray bars) and PF4 release from platelets (hatched bars) after plasma platelet stimulation with agonists under aggregating conditions. (B) Surface P-selectin expression (white bars) and αII/β3 receptor activation (black bars) after plasma platelet stimulation with various agonists under nonaggregating conditions. Each chemokine shown was tested at 100 nmol/L; ADP was tested at 10 μmol/L, and TRAP was tested at 25 μmol/L. Data represents the mean ± SEM for 3 experiments completed in duplicate.
