Effects of indinavir or saquinavir on T-cell survival and HIV-1 inhibition.

Dose-dependent effects of indinavir or saquinavir on T-cell survival (○) and HIV-1 inhibition (▵). Results show the mean ± SD of triplicate cultures of net gain of viable cells or percentage HIV-1 p24 inhibition in 3 representative PBMCs of untreated patients A (A and B), B (C and D), and C (E and F) in the absence or the presence of different concentrations of each of the 2 protease inhibitors.