Fig. 7.
![Fig. 7. Neutralizing antibodies to TNF and IFNγ block [CD4XL/CD3]-induced T-cell apoptosis. / CD4XL/CD3 treatment was performed in PBTs in the absence or presence of various concentrations of anti-IFNγ antibody (open circles) or anti-TNFα antibody (closed circles). Data obtained from the simultaneous addition of anti-IFNγ antibody (1.0 μg/mL) and anti-TNFα antibody (3.0 μg/mL) are indicated as open squares. Apoptosis was determined by annexin V labeling. Data represent 2 independent experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/96/1/10.1182_blood.v96.1.195/4/bloo01351007x.jpeg?Expires=1724257637&Signature=lB4o5mGaM5CGoBBJPzlrDp71vTnrnIFQ~GssVaJXtq~GFWTVHtTuW7Z88P0i5Ao3GbMb1CspW-pzTvZDQtB2UYT1zrF~Zyb5mz21Howu0GZ2lEBDIXwftl8oO-jvQc2OBpw5m27xgC5QYZDjDzrAMPrbFTo90O5fYzu8AZHhZdb9sT-ma44T-PeZk8Zjy2ysTNCqPEh7X4K1qCA~Su~YRGFL00zqgSEdEDOZxARuiGohEGXe73g4mjW0HLGX8M1mQYBP34HyPGoIuxoyQm-KVungSczpMZGP73fx4R2O6u-1ObPO5Z9UROiXHFXWP9FnA1P2NeD4q0G~PdOeab2Sag__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Neutralizing antibodies to TNF and IFNγ block [CD4XL/CD3]-induced T-cell apoptosis.
CD4XL/CD3 treatment was performed in PBTs in the absence or presence of various concentrations of anti-IFNγ antibody (open circles) or anti-TNFα antibody (closed circles). Data obtained from the simultaneous addition of anti-IFNγ antibody (1.0 μg/mL) and anti-TNFα antibody (3.0 μg/mL) are indicated as open squares. Apoptosis was determined by annexin V labeling. Data represent 2 independent experiments.
