Fig. 1.
![Fig. 1. [CD4XL/CD3]-induced lymphocyte apoptosis is blocked by soluble Fas or by anti-FasL mAb. / Soluble Fas (sFas: closed circles) or 4H9 (closed squares) was added at the indicated concentrations (μg/mL) to the cultures of CD4 cross-linked T cells plus anti-CD3 mAb ([CD4XL/CD3]: open square), and apoptosis was evaluated by annexin V binding. Apoptotic populations of CD4XL alone (open circle) and/or anti-CD3/CD28 mAbs (open triangle) are also indicated. Data represent mean ± SD of 3 experiments. *Significantly (P < .001) different from CD4XL/CD3 samples.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/96/1/10.1182_blood.v96.1.195/4/bloo01351001x.jpeg?Expires=1724257509&Signature=TvykSzI84Z7AK8zcY6MDvcQw8Pc6T70HaZjtCIxKmybmfJiKEGRySBYTqdO7YBgyjmkMt5Hy0Ix1PDLvZdcyOE5RBGJyhahA~u4irhSfun6HW0rwHISfjW7Bz6G8endaZ6aZbRV1pmGSp~jaKxxR94g68emTjCtI5hYpQVz2ZChxAofpgrAw5F3B-gfnUBu7KIcp8JNKb~CLNbTd7qIvdXDZNQbtiTqhBQJSFbddMsH9qk5X49iHKUUuXQdLcPTQlILQeSM7RG68wGyL-B~v7C6OISzak0mYWG-Spg22Srh8zq8-XCfdvV7iVEN8e03RMyNcnJ6aNImeMQ6XTf~-EA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
[CD4XL/CD3]-induced lymphocyte apoptosis is blocked by soluble Fas or by anti-FasL mAb.
Soluble Fas (sFas: closed circles) or 4H9 (closed squares) was added at the indicated concentrations (μg/mL) to the cultures of CD4 cross-linked T cells plus anti-CD3 mAb ([CD4XL/CD3]: open square), and apoptosis was evaluated by annexin V binding. Apoptotic populations of CD4XL alone (open circle) and/or anti-CD3/CD28 mAbs (open triangle) are also indicated. Data represent mean ± SD of 3 experiments. *Significantly (P < .001) different from CD4XL/CD3 samples.
