Fig. 3.
High levels of ubiquitinated nuclear proteins in B-CLL.
Cytoplasmic (A) or nuclear (B) ubiquitin-conjugated proteins of untreated PBL (lane 1) or untreated B-CLL cells (lane 2) were determined by Western blot in 10% SDS-PAGE. An equal amount of protein derived from 1.5 × 106 cells was deposited in each lane. The results represent analyses of cells from 10 different patients and 10 different normal donors.
