Fig. 7.
Fig. 7. Leu262Proβ3 is expressed in a complex with αv in 293 cells. / Untransfected (C) 293 cells or cells stably transfected with WT β3 or Leu262Proβ3 (LD) were analyzed by flow cytometry. The mean fluorescence for each cell line is shown. The 2 left-hand panels show binding of a negative-control antibody (nonimmune mouse IgG) and a positive-control antibody (polyclonal anti-β1). The 2 right-hand panels show the results of flow cytometry and immunoprecipitation of biotin surface-labeled cells with antibodies against β3 (AP3) or the αvβ3complex (LM609). The positions of αv and β3are indicated.

Leu262Proβ3 is expressed in a complex with αv in 293 cells.

Untransfected (C) 293 cells or cells stably transfected with WT β3 or Leu262Proβ3 (LD) were analyzed by flow cytometry. The mean fluorescence for each cell line is shown. The 2 left-hand panels show binding of a negative-control antibody (nonimmune mouse IgG) and a positive-control antibody (polyclonal anti-β1). The 2 right-hand panels show the results of flow cytometry and immunoprecipitation of biotin surface-labeled cells with antibodies against β3 (AP3) or the αvβ3complex (LM609). The positions of αv and β3are indicated.

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