Effect of various differentiating agents on the susceptibility of MER cells to lysis by IL-2–activated PBMCs.

MER cells were treated with PWM (1%), PHA (1μg/mL), ConA (1μg/mL), Protein A (.05 μg/mL), anti-IgG (10 μg/mL), IL-2 (100 U/mL), and IFNγ (10 U/mL)—or the combination of IL-2 and IFNγ—for 3 days. These cells were then washed extensively and used as targets in 4-hour ⁵¹Cr release assays. The E:T ratio was 30:1. The data represent the mean values ± SEM of 4 individual experiments. *P < .005; ⁺P < .05