BPI inhibits in vitro angiogenesis in a collagen matrix.

BCEs were cultured on gelatin-coated Cytodex-3 beads in a collagen matrix. Sprouting was induced by addition of 20 ng/mL bFGF (panel A). Panel B shows sprouting of BCEs in the presence of 20 ng/mL bFGF and 1.8 μmol/L BPI. Quantification of results was performed by NIH-image software (n = 3, *P < .013).