Fig. 3.
Effect of blocking antibodies to MHC class I on CTL-mediated apoptosis of CLL B cells.
CLL target cells were preincubated with 10 μg/mL anti–MHC class I mAb W6/32 for 1 hour prior to initiation of the CTL assay. CTL-mediated apoptosis of resting (left) and CD40-activated (right) CLL B target cells with no pretreatment (darkened circles) or preincubated with W6/32 mAb (open circles) at an E/T ratio of 10:1. Data are representative of 1 out of 4 experiments performed with similar results.
