Recombinant REDK can phosphorylate myelin basic protein and histones.

Nuclear protein extracts from log cells stably transfected with a tagged, recombinant REDK-S (clone S9) were immunoprecipitated by the T7-tag-specific sera. Immunoprecipitates were incubated with P-33-ATP and substrates to assess activity. Samples were collected in the linear range and analyzed as previously.