Age-related changes of absolute numbers of naive CD95⁻CD28⁺ (○) and CD95⁺CD28⁻ (▴) T cells.

Absolute numbers of CD95⁻ and CD28⁻T cells among CD3⁺ cells from 96 donors were plotted as individual data points. R and P values were calculated by linear regression analysis. While CD95⁻ T cells significantly decreased with age, CD28⁻ T cells simultaneously increased.