Immunohistochemical detection of IL-16 in DTH footpads.

The section of mBSA- and PBS-challenged footpads (A and B, respectively) was immunohistochemically analyzed for the expression of IL-16 using anti-IL-16 (17.1) 24 hours after the Ag challenge. No staining was observed when an isotype-matched control mAb (MOPS-21) was used (data not shown). Similar results were obtained in 3 independent experiments.