Microvessel density on day 0 compared with day 16 and day 16 compared with complete remission.

(A) Microvessel density on day 16 (d 16) of induction chemotherapy compared with presentation (d 0). (B) Pair comparisons of microvessel density between day 16 (d 16) of induction chemotherapy and the time of complete remission (CR). In (A) “blast –” refers to patients without residual leukemic blast infiltration and “blast +” to patients with at least 5% residual leukemic blast infiltration. In A and B, each pair of dots linked by a line represents the values from an individual patient. The difference in microvessel counts between day 0 and day 16 in the “blast –” group was statistically significant (P < .001, Wilcoxon test), in contrast to the “blast +” group (P = .052). No differences were found by Wilcoxon test (P = .185) between day 16 and the time of complete remission.