Fig. 1.
Fig. 1. Restriction map of the transgenic construct CD19-IE. / MHC class II I-Eαd cDNA (striped box) was placed under the control of a human CD19 promoter containing DNA segment (gray box). The rabbit β-globin gene fragment providing the cDNA with an intron and a polyadenylation signal (A(n)) is displayed as a white box. X, XhoI; N, NotI; B,BamHI; E, EcoRI; S, SpeI; restriction sites in parenthesis () have been destroyed by blunt-end cloning.

Restriction map of the transgenic construct CD19-IE.

MHC class II I-Eαd cDNA (striped box) was placed under the control of a human CD19 promoter containing DNA segment (gray box). The rabbit β-globin gene fragment providing the cDNA with an intron and a polyadenylation signal (A(n)) is displayed as a white box. X, XhoI; N, NotI; B,BamHI; E, EcoRI; S, SpeI; restriction sites in parenthesis () have been destroyed by blunt-end cloning.

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