Fig. 5.
In vivo protection of bone marrow progenitor cells from TMTX and NBMPR-P treatment.
Mice transplanted with untransduced (N) or MeiIRG (e)-transduced BM cells were treated daily for 5 days with 80 mg/kg Neutrexin and 20 mg/kg NBMPR 25 weeks after transplantation. BM cells were harvested from femurs of treated mice 24 hours after final drug treatment, and the volume equivalent of 1 × 105 cells, from untreated animals, were plated in 3 mL methylcellulose. Colonies containing more than 50 cells were scored 7 days later and are expressed as a percentage of the colony number observed from untreated control mice.
