Effect of CTX versus poly (I:C) injection on Ly-6C expression in spleen lymphocytes at different times after treatment.

Seven- to 8-week-old DBA/2 mice were injected intraperitoneally with CTX (83 mg/kg) (dotted bars), poly (I:C) (0.15 mg/mouse) (striped bars), or saline (white bars). At different time intervals, spleens were taken and cells were stained for Ly-6C expression and processed for FACS analysis. There were 3 mice per group. The data show the mean (± SE) of the percentage of Ly-6C^hi cells with respect to the number of total spleen lymphocytes. *P ≤ .05 versus controls; **P ≤ .001 versus controls.