Fig. 11.
![Fig. 11. Effects of overexpression of Bcl-2 in Jurkat cells on their susceptibility to tumor-mediated DNA degradation. / Bcl-2 or control Neo-transfected Jurkat cells were labeled with [3H]TdR and coincubated with tumor cells at a tumor-to-lymphocyte cell ratio of 40:1. As controls, these cells were treated with agonistic anti-Fas Ab (CH-11, 200 ng/mL) or VP-16 (20 μmol/L). Target cell apoptosis was determined at the indicated time points by measuring loss in 3H-labeled DNA in the JAM assay. The error bars represent the SEM of 8 replicates.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/95/6/10.1182_blood.v95.6.2015/6/bloo00630011x.jpeg?Expires=1724229173&Signature=QNJUJKobDX9Hfok-X7Q~JHghZILXcvN5JBVye4g8Obm48veielGnN74vdH4YLWOXJL-fFm4DDduC45u~NyjFxgJ4xmgntXB0xyWeOuqmf7D9iX-x1-Ysn7vrZbVbpnkXWXHZCYoXqyLd4-r0wXgYv85vIFwjdYGYI5v1aR~3bn59f7xfmX0OnR3EEct3WozkZSlDvtbGaO6TvxN8UcadjwROQJlP17UqV2u8WTMaJENeSrkolUYHqTPzXl1QGRjJY~4tz2zjFex2K0lhQAvcJ0WpACOvm0vJ03kAqDSq2tNUleIVN4cy01kXIOu4N0jnpmhZjuSw1aEJMymx1Kkd9Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effects of overexpression of Bcl-2 in Jurkat cells on their susceptibility to tumor-mediated DNA degradation.
Bcl-2 or control Neo-transfected Jurkat cells were labeled with [3H]TdR and coincubated with tumor cells at a tumor-to-lymphocyte cell ratio of 40:1. As controls, these cells were treated with agonistic anti-Fas Ab (CH-11, 200 ng/mL) or VP-16 (20 μmol/L). Target cell apoptosis was determined at the indicated time points by measuring loss in 3H-labeled DNA in the JAM assay. The error bars represent the SEM of 8 replicates.
