Fig. 5.
Infusion of ▵MGMT-transduced cells protects mice from cumulative myelosuppression.
Blood counts from BG- and BCNU-treated mice were monitored for 70 to 80 days. The first treatment (dashed line) was performed 3 weeks after the infusion of bone marrow cells, and subsequent treatments were administered every 4 weeks. Each value represents the mean of 3 mice, except *, which was obtained from 1 surviving normal mouse. Error bars represent SD of mean. ▴, 100 × 104 cohort; •, 25 × 104 cohort; ▪, normal mice.
