BG and BCNU resistance in transduced CFU.

After transduction, bone marrow was mixed with untransduced cells at final ratios of 1:4 and 1:20. The cells were treated with 20 μmol/L BG and 0 to 40 μmol/L BCNU then plated in methylcellulose, and CFU growth was scored. Error bars represent mean ± SD. ▪, ΔMGMT transduced; ⧫, 25% ΔMGMT transduced; •, 5% ΔMGMT transduced; ▴, untransduced.