IL-12 induced cytotoxicity in cytokine-primed NK cells.

NK cells were primed with or without cytokines as indicated for 3 days. Cells were then washed and incubated with or without IL-12 for 18 hours. Specific cytotoxicity of the NK cells against Colo cells at a 5:1 ratio was tested. A summary of experiments with NK cells from 3 different donors is presented.