T-cell lymphoma after intravenous infection with herpesvirus saimiri C488 of naive cynomolgus monkeys.

The tissue sections were stained with hematoxilin/eosin. Upper panel: Lymph node showing peripheral pleomorphic T-cell lymphoma with medium-sized and large blasts containing vesicular nuclei and prominent nucleoli (original magnification ×100). Central panel: Immunostaining of the medium-sized and large blasts and some accompanying small lymphocytes for CD3 (original magnification ×63). Lower panel: Infiltration of the portal tracts of the liver by the blast cells (original magnification ×40).