Expression of human Aγ-globin mRNA in transgenic mice containing the BGT 64 construct.

S1 nuclease analysis on fetal liver RNA of 15.5-day founder transgenic mice showing that the BGT64 is expressed at significant levels in 13 of the 17 transgenic mice. These data show that the AT-rich region in β-globin intron 2 is necessary for the single-copy expression characteristics of BGT50. Abbreviations as described in Figure 3.