Pretreatment with DEX alters the cytokine secretion profile of CD40-triggered DCs.

DEX-exposed or control immature DCs were left in culture without further treatment or stimulated with the CD8-CD40L fusion protein. Culture supernatants were harvested 48 hours later, and IL-10, IL-12p40, and IL-12p70 secretion were analyzed by specific enzyme-linked immunosorbent assay. Data are representative from 6 independent experiments.