Wild-type and mutant EKLF CAT transgenic constructs.

The mouse EKLF promoter from −1150 to +60 was fused to the CAT reporter gene. The nucleotide sequence for GATA-E box-GATA motif is shown above the wild-type construct. Each consensus-binding site is underlined. Asterisks mark the mutations in subsequent constructs; the nucleotide changes are shown in italics.