Fig. 2.
Allele-specific oligonucleotide hybridization for IVS4.

Allele-specific oligonucleotide hybridization for IVS4.

Hybridization of the wild-type or mutant oligonucleotide to DNAs from the FA patients with the IVS4 mutation (P1, P3, P4, P5, P6, and P7) and control cells. 4510C cells are homozygous for the IVS4 mutation; FA239 cells are heterozygous (IVS4/wt) for this segment; and N indicates normal control.

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