Hematologic variables and phenotypic expression of 4.1R deficiency in families A and B.

Note the unusually low elliptocyte counts in heterozygous members of family B compared with the typical 100% hereditary elliptocytosis HE in heterozygous members of family A; n.e. indicates not examined. Family C, which was described previously,23,24 is included for comparison. Numbers to right of circles and squares represent, in descending order, percent of elliptocytes; amount of hemoglobin, g/dL; and the reticulocyte count as a percentage of the whole blood cell population. □, normal 4.1R; ▥, 4.1R Fier; ▨, 4.1R Coimbra; ▧, uncharacterized 4.1R mutation; , 4.1R Presles.