Microsatellite analysis of MSH2−/− murine lymphoma single cell clones.

(A) Examples of analysis of DNA from single cell clones derived from the R25 cell line at D6Mit8 marker. No microsatellite instability is seen. (B) Examples of analysis of DNA from single cell clones derived from the L15 cell line at D8Mit14 marker. Novel microsatellite alleles are present in 2 of the clones (lanes 2 and 6).