Microsatellite analysis of MSH2−/− murine lymphomas.

(A) Examples of the analysis of DNA from paired nonmalignant (N) and whole lymphoma tumor specimens (T) at the D5Mit10 marker. Novel microsatellite alleles are present in 1 tumor specimen. (B) Examples of the analysis of DNA from paired normal tissue (N) and whole tumor tissue (T) at the D7Mit12 marker. No microsatellite instability is seen.